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Alexandra Chivu
Verified
Editor-in-Chief, 9AM News
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By Alexandra Chivu Verified, Abderhman Abuhashem, Michelle M. Leger, Brent A Basso| bioRxiv@ AbstractPromoter-proximal pausing of RNA polymerase II (Pol II) is a key regulatory step during transcription. Despite the central role of pausing in gene regulation, we do not understand the evolutionary processes that led to the emergence of Pol II pausing or its transition to a rate-limiting step actively controlled by transcription factors. Here we analyzed transcription in species across the tree of life.
By Alexandra Chivu Verified, Abderhman Abuhashem, Gilad Barshad, Edward J Rice| bioRxiv@ Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
By Alexandra Chivu Verified, Abderhman Abuhashem, Michelle M. Leger, Brent A Basso| bioRxiv@ AbstractPromoter-proximal pausing of RNA polymerase II (Pol II) is a key regulatory step during transcription. Despite the central role of pausing in gene regulation, we do not understand the evolutionary processes that led to the emergence of Pol II pausing or its transition to a rate-limiting step actively controlled by transcription factors. Here we analyzed transcription in species across the tree of life.
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