Austin Irwin - Profile and Journalist Details
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Verified
Associate Editor, Car and Driver
Beats
Aerospace , Autos , Mobility
Content
Mutations in the Transcriptional Regulator MeCP2 Severely Impact Key Cellular and Molecular Signatures of Human Astrocytes During Maturation
By Jialin Sun, Sivan Osenberg, Austin Irwin Verified, Li-Hua Ma| Texas Medical Center@ KeywordsHumans, Astrocytes, Methyl-CpG-Binding Protein 2, Rett Syndrome, Neurons, Brain, MutationAbstractMutations in the MECP2 gene underlie a spectrum of neurodevelopmental disorders, most commonly Rett syndrome (RTT). We ask whether MECP2 mutations interfere with human astrocyte developmental maturation, thereby affecting their ability to support neurons.
By Austin Irwin Verified| Car and Driver Verified From the March/April 2025 issue of Car and Driver. Lap Time: 3:15.6Class: LL1 | Base: $38,470 | As Tested: $39,065 Power and Weight: 181 hp • 2350 lb • 13.0 lb/hp Tires: Bridgestone Potenza S001; 205/45R-17 84WWhen a Mazda Miata comes to Lightning Lap, it's always a David among Goliaths. This year, two cars in the competition each produce over 1000 horsepower. This MX-5 Miata Club? It has 181 adorable little ponies. And talk about a lightweight.
Mutations in the Transcriptional Regulator MeCP2 Severely Impact Key Cellular and Molecular Signatures of Human Astrocytes During Maturation
By Jialin Sun, Sivan Osenberg, Austin Irwin Verified, Li-Hua Ma| Texas Medical Center@ KeywordsHumans, Astrocytes, Methyl-CpG-Binding Protein 2, Rett Syndrome, Neurons, Brain, MutationAbstractMutations in the MECP2 gene underlie a spectrum of neurodevelopmental disorders, most commonly Rett syndrome (RTT). We ask whether MECP2 mutations interfere with human astrocyte developmental maturation, thereby affecting their ability to support neurons.
Company Info
Car and Driver
Ann Arbor, Michigan, United States
'+1 800-348-5711