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Brian Thomas
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By Brian Thomas Verified, Xue Bai, Benjamin Cryer, Sydney M Escobar| bioRxiv@ AbstractThe discovery of immune checkpoints and the rapid growth of immuno-oncology (IO) have sparked tremendous efforts to utilize the immune system to treat a wide range of cancer types/subtypes. While the major focus of IO over the past decades has been to manipulate the adaptive immune system, recent attention has been given to manipulating the innate immune system to treat cancer and/or to enhance adaptive responses.
By Brian Thomas Verified, Trupti Joshi, Mark Daniels, Sania Z Awan| bioRxiv@ AbstractNon-small cell lung cancer (NSCLC) adenocarcinoma (LUAD) is a leading cause of death worldwide. Activating mutations in the tyrosine kinase domain of the oncogene epidermal growth factor receptor (EGFR) are responsible for ~10-50% of all LUAD cases. Although EGFR tyrosine kinase inhibitors (TKIs) have been effective in prolonging NSCLC patient survival and quality of life, acquired resistance mechanisms and disease progression are inevitable.
By Brian Thomas Verified| The National Law Review Verified Iowa is on the brink of becoming the next state to embrace captive insurance companies. On April 24, the Iowa Senate unanimously passed Senate File 549 (SF 549), as amended, “a bill for an act relating to captive insurance companies,” which the House passed earlier in April. Governor Kim Reynolds is expected to sign the bill into law, making Iowa the thirty-sixth United States jurisdiction (including the District of Columbia) to adopt a captive insurance statute.
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Brian Thomas
Cincinnati, Ohio, United States
+1 513-749-5500