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Caitlin Francis
Verified
Anchor and Reporter, WFSB-TV (Hartford, CT)
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Outdoor LegalTravel
Content
By Martin Lange, Caitlin Francis Verified, Jessica Furtado, Young-Bum Kim| bioRxiv@ AbstractBackground: The Rho kinases 1 and 2 (ROCK1/2) are serine-threonine specific protein kinases that control actin cytoskeleton dynamics. They are expressed in all cells throughout the body, including cardiomyocytes, smooth muscle cells and endothelial cells, and intimately involved in cardiovascular health and disease. Pharmacological ROCK inhibition is beneficial in mouse models of hypertension, atherosclerosis, and neointimal thickening that display overactivated ROCK.
By Caitlin Francis Verified, Makenzie L Bell, Marina M Skripnichuk, Erich J. Kushner| Wiley Online Library Verified CONFLICT OF INTEREST STATEMENT Authors declare no competing interests. No part of this manuscript was created by AI or any LLMs. Supporting Information Filename Description micc12831-sup-0001-DataS1.pdfPDF document, 1.3 MB Data S1: micc12831-sup-0002-MovieS1.aviAVI video, 484.9 KB Movie S1. micc12831-sup-0003-MovieS2.aviAVI video, 454.6 KB Movie S2. micc12831-sup-0004-MovieS3.aviAVI video, 1.3 MB Movie S3.
By Martin Lange, Caitlin Francis Verified, Jessica Furtado, Young-Bum Kim| bioRxiv@ AbstractBackground: The Rho kinases 1 and 2 (ROCK1/2) are serine-threonine specific protein kinases that control actin cytoskeleton dynamics. They are expressed in all cells throughout the body, including cardiomyocytes, smooth muscle cells and endothelial cells, and intimately involved in cardiovascular health and disease. Pharmacological ROCK inhibition is beneficial in mouse models of hypertension, atherosclerosis, and neointimal thickening that display overactivated ROCK.
Company Info
WFSB-TV (Hartford, CT)
Rocky Hill, Connecticut, United States
+1 860-728-3333