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Verified
News Anchor, CJSB (Woodstock, NB)
Fredericton
Beats
Politics, Economy
Content
A PARP14/TARG1-Regulated RACK1 MARylation Cycle Drives Stress Granule Dynamics in Ovarian Cancer Cells
By Sridevi Challa, Amy Gong, Charles Renshaw Verified, Hyung Bum Kim| bioRxiv@ AbstractMono(ADP-ribosyl)ation (MARylation), a post-translational modification (PTM) of proteins, is emerging as a critical regulator of ribosome function and translation. Herein, we demonstrate that RACK1, a member of the tryptophan-aspartate repeat (WD-repeat) family of proteins and an integral component of the ribosome, is MARylated by the mono(ADP-ribosyl) transferase (MART) PARP14 in ovarian cancer cells.
By Charles Renshaw Verified| Bathurst's BOUNCE 104.9 Verified The Keswick RCMP is asking the public for help as they attempt to locate a vehicle of interest in connection with an incident at a residence in Pepper Creek last month. Officers responded early in the evening on June 26th to an incident at a residence on Country Wood Lane. Police say they are looking for a white sedan or hatchback with dark tinted windows in connection to that investigation.
A PARP14/TARG1-Regulated RACK1 MARylation Cycle Drives Stress Granule Dynamics in Ovarian Cancer Cells
By Sridevi Challa, Amy Gong, Charles Renshaw Verified, Hyung Bum Kim| bioRxiv@ AbstractMono(ADP-ribosyl)ation (MARylation), a post-translational modification (PTM) of proteins, is emerging as a critical regulator of ribosome function and translation. Herein, we demonstrate that RACK1, a member of the tryptophan-aspartate repeat (WD-repeat) family of proteins and an integral component of the ribosome, is MARylated by the mono(ADP-ribosyl) transferase (MART) PARP14 in ovarian cancer cells.
Company Info
CJSB (Woodstock, NB)