Daniel G.J. Smethurst - Profile and Journalist Details
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Technical Writer, Oxford Nanopore Technologies
Oxford
Beats
climate changeliterature energy colonialism
Content
Interchangeable utilization of metals: new perspectives on the impacts of metal ions employed in ancient and extant biomolecules
By Daniel G.J. Smethurst, Natalia Shcherbik| The Journal of Biological Chemistry Verified AbstractMetal ions provide considerable functionality across biological systems, and their utilization within biomolecules has adapted through changes in the chemical environment to maintain the activity they facilitate. While ancient Earth’s atmosphere was rich in iron and manganese and low in oxygen, periods of atmospheric oxygenation significantly altered the availability of certain metal ions, resulting in ion replacement within biomolecules.
By Nikolay Kovalev, Dimitri G. Pestov, Daniel G.J. Smethurst, Erica R. McKenzie| The Journal of Biological Chemistry Verified Daniel G.J. Smethurst1, Nikolay Kovalev1, Erica R. McKenzie2, Dimitri G.
Interchangeable utilization of metals: new perspectives on the impacts of metal ions employed in ancient and extant biomolecules
By Daniel G.J. Smethurst, Natalia Shcherbik| The Journal of Biological Chemistry Verified AbstractMetal ions provide considerable functionality across biological systems, and their utilization within biomolecules has adapted through changes in the chemical environment to maintain the activity they facilitate. While ancient Earth’s atmosphere was rich in iron and manganese and low in oxygen, periods of atmospheric oxygenation significantly altered the availability of certain metal ions, resulting in ion replacement within biomolecules.
Company Info
Oxford Nanopore Technologies
Oxford Nanopore Technologies is a UK-based biotechnology company founded in 2005, focused on nanopore-based molecular sensing systems for analyzing DNA, RNA, proteins, and small molecules. Headquartered in Oxford, the company offers a range of sequencing devices and services that facilitate real-time, scalable analysis for both research and clinical applications. Their product lineup includes the MinION, a portable sequencer for real-time DNA/RNA sequencing; the GridION X5, a desktop system for larger data generation; and the PromethION, a high-throughput sequencer for extensive projects. Additional offerings include the Flongle adapter for rapid analysis, the VolTRAX automated sample preparation device, and the SmidgION, a mobile phone-compatible sequencer currently in development. Oxford Nanopore also provides training, certification, and technical support, and collaborates with academic and industry partners to enhance genomic and medical applications. Their proprietary nanopore sequencing technology enables long-read sequencing without PCR amplification, supporting diverse applications from microbial genomics to human genetics.
Oxford, England, United Kingdom
+44 845 034 7900
Founded: 2005