David Herrmann - Profile and Journalist Details

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Total articles 6

• Using rotational integration of oblique interferometric scattering (RO-iSCAT) to track axial spatiotemporal responses of membrane protrusions

  By Junyu Liu, David Herrmann, Paul Timpson, Woei Ming Lee| bioRxiv@ AbstractDespite the crucial importance of dynamic membrane protrusions for understanding phagocytosis, cellular communication and mechanobiology, current imaging modalities struggle to quantitatively track their real-time, 3D spatiotemporal dynamics with sufficient molecular specificity and minimal perturbation. Many membrane protrusions studies still utilize confocal microscopy where its axial resolution and high phototoxicity remains a key limiting factor for live axial imaging.

  By Junyu Liu, David Herrmann, Paul Timpson, Woei Ming Lee · bioRxiv

  Mar. 25, 2025

• Imaging throughput of compact handheld microscopes for quantitative single cell studies

  By Sophie Bulloch, Tienan Xu, David Herrmann, Paul Timpson| bioRxiv@ AbstractIncuscopes, incubator-compatible microscopes, are crucial for live single-cell imaging studies that spans several hours to days. However, traditional microscopy prioritize high-resolution imaging performance over throughput, neglecting efficient live-cell image sampling. This study challenges existing spatial bandwidth product (field of view/optical resolution) criteria for image sampling for live cells.

  By Sophie Bulloch, Tienan Xu, David Herrmann, Paul Timpson · bioRxiv

  Mar. 25, 2025

• Using rotational integration of oblique interferometric scattering (RO-iSCAT) to track axial spatiotemporal responses of membrane protrusions

  By Junyu Liu, David Herrmann, Paul Timpson, Woei Ming Lee| bioRxiv@ AbstractDespite the crucial importance of dynamic membrane protrusions for understanding phagocytosis, cellular communication and mechanobiology, current imaging modalities struggle to quantitatively track their real-time, 3D spatiotemporal dynamics with sufficient molecular specificity and minimal perturbation. Many membrane protrusions studies still utilize confocal microscopy where its axial resolution and high phototoxicity remains a key limiting factor for live axial imaging.

  By Junyu Liu, David Herrmann, Paul Timpson, Woei Ming Lee · bioRxiv

  Mar. 25, 2025

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KWCH-TV (Wichita, KS)