Eduardo A. Albornoz - Profile and Journalist Details
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Contributor, Travel by Mexico Blog
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Interaction of Gut-Microbial Amyloids with Endogenous Amyloids can Drives Microglial Hyperactivity and Neuroinflammation in Alzheimers Disease
By Ibrahim Javed, Thomas Davis, Helen Forgham, Eduardo A. Albornoz| bioRxiv@ AbstractGut bacteria have emerged as silent drivers in the pathology of Alzheimers disease (AD). They also make amyloids with structure analogue to pathological amyloids and have potential to cross-seed and propagate in a prion-like manner. AD is characterised by the accumulation of mature extracellular Amyloid-β (Aβ) plaques which are surrounded by inflammatory microglia
Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology - Nature Aging
By Julio Aguado, Atefeh Taherian Fard, Eduardo A. Albornoz, Alexander Tyshkovskiy, Marius Schwabenland, Benjamin Liang, Lianli Peng, Pranesh Padmanabhan, Rhys Parry, Thomas Davis, Marco Prinz, Bertram R Bengsch, Vadim N. Gladyshev, Trent M Woodruff| Nature Verified AbstractAging is a major risk factor for neurodegenerative diseases, and coronavirus disease 2019 (COVID-19) is linked to severe neurological manifestations. Senescent cells contribute to brain aging, but the impact of virus-induced senescence on neuropathologies is unknown. Here we show that senescent cells accumulate in aged human brain organoids and that senolytics reduce age-related inflammation and rejuvenate transcriptomic aging clocks
Company Info
Travel by Mexico Blog