Erik Osterman - Profile and Journalist Details

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• Prognostic genome and transcriptome signatures in colorectal cancers - Nature

  By Luis Nunes, Luís A Nunes, Fuqiang Li, Per-Henrik Edqvist, Anna Löfgren-Burström, Carl Zingmark, Erik Osterman, Erik Österman, Emerik Osterlund, Inês Neves, Malin Enblad, Fredrik Pontén, Richard Palmqvist, Xun Xu, Mathias Uhlén, Kui Wu, Bengt Glimelius, Cong Lin, Chatarina Larsson| Nature Verified AbstractColorectal cancer is caused by a sequence of somatic genomic alterations affecting driver genes in core cancer pathways1. Here, to understand the functional and prognostic impact of cancer-causing somatic mutations, we analysed the whole genomes and transcriptomes of 1,063 primary colorectal cancers in a population-based cohort with long-term follow-up. From the 96 mutated driver genes, 9 were not previously implicated in colorectal cancer and 24 had not been linked to any cancer.

  By Luis Nunes, Luís A Nunes, Fuqiang Li, Per-Henrik Edqvist, Anna Löfgren-Burström, Carl Zingmark, Erik Osterman, Erik Österman, Emerik Osterlund, Inês Neves, Malin Enblad, Fredrik Pontén, Richard Palmqvist, Xun Xu, Mathias Uhlén, Kui Wu, Bengt Glimelius, Cong Lin, Chatarina Larsson · Nature

  Aug. 07, 2024

• Prognostic genome and transcriptome signatures in colorectal cancers - Nature

  By Luis Nunes, Luís A Nunes, Fuqiang Li, Per-Henrik Edqvist, Anna Löfgren-Burström, Carl Zingmark, Erik Osterman, Erik Österman, Emerik Osterlund, Inês Neves, Malin Enblad, Fredrik Pontén, Richard Palmqvist, Xun Xu, Mathias Uhlén, Kui Wu, Bengt Glimelius, Cong Lin, Chatarina Larsson| Nature Verified AbstractColorectal cancer is caused by a sequence of somatic genomic alterations affecting driver genes in core cancer pathways1. Here, to understand the functional and prognostic impact of cancer-causing somatic mutations, we analysed the whole genomes and transcriptomes of 1,063 primary colorectal cancers in a population-based cohort with long-term follow-up. From the 96 mutated driver genes, 9 were not previously implicated in colorectal cancer and 24 had not been linked to any cancer.

  By Luis Nunes, Luís A Nunes, Fuqiang Li, Per-Henrik Edqvist, Anna Löfgren-Burström, Carl Zingmark, Erik Osterman, Erik Österman, Emerik Osterlund, Inês Neves, Malin Enblad, Fredrik Pontén, Richard Palmqvist, Xun Xu, Mathias Uhlén, Kui Wu, Bengt Glimelius, Cong Lin, Chatarina Larsson · Nature

  Aug. 07, 2024

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