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Fabio Arias
Verified
Asunción
Beats
Blockchain,Covers: cryptocurrencies technology sector, municipal bonds personal finance, capital and equity markets biotech sector, financial sector
Planes, boats, trains
Content
Inhibition of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis - Nature Metabolism
By Sandeep Das, Alexandra C Finney, Sumit Anand, Alia Ghrayeb, Kelley G. Núñez, Fabio Arias, M. Peyton McKinney, Chowdhury S. Abdullah, Andrew Yurochko, Christopher G. Kevil, Babak Razani, Erin H. Seeley, Gretchen Galliano, Bo Wei, Iqbal Mahmud, Ida L. Surakka, Minerva T. Garcia-Barrio, Philip L. Lorenzi, Eyal Gottlieb, Eduardo Salido, Jifeng Zhang, A. Orr, Ari Cohen Verified, Brenna H. Pearson-Gallion, Jose A. Gomez-Vidal, Elizabeth D. Cockerham, Monica Diaz-Gavilan, Paul T. Thevenot, Arif Yurdagul Jr| Nature Verified AbstractThe incidence of metabolic dysfunction-associated steatohepatitis (MASH) is on the rise, and with limited pharmacological therapy available, identification of new metabolic targets is urgently needed. Oxalate is a terminal metabolite produced from glyoxylate by hepatic lactate dehydrogenase (LDHA). The liver-specific alanine-glyoxylate aminotransferase (AGXT) detoxifies glyoxylate, preventing oxalate accumulation.
Inhibition of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis - Nature Metabolism
By Sandeep Das, Alexandra C Finney, Sumit Anand, Alia Ghrayeb, Kelley G. Núñez, Fabio Arias, M. Peyton McKinney, Chowdhury S. Abdullah, Andrew Yurochko, Christopher G. Kevil, Babak Razani, Erin H. Seeley, Gretchen Galliano, Bo Wei, Iqbal Mahmud, Ida L. Surakka, Minerva T. Garcia-Barrio, Philip L. Lorenzi, Eyal Gottlieb, Eduardo Salido, Jifeng Zhang, A. Orr, Ari Cohen Verified, Brenna H. Pearson-Gallion, Jose A. Gomez-Vidal, Elizabeth D. Cockerham, Monica Diaz-Gavilan, Paul T. Thevenot, Arif Yurdagul Jr| Nature Verified AbstractThe incidence of metabolic dysfunction-associated steatohepatitis (MASH) is on the rise, and with limited pharmacological therapy available, identification of new metabolic targets is urgently needed. Oxalate is a terminal metabolite produced from glyoxylate by hepatic lactate dehydrogenase (LDHA). The liver-specific alanine-glyoxylate aminotransferase (AGXT) detoxifies glyoxylate, preventing oxalate accumulation.
Company Info
Asunción, Paraguay