Guo Rui - Profile and Journalist Details
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Guo Rui
Verified
Reporter, South China Morning Post
Guangzhou
Beats
the budget
Content
Application of COMSOL Multiphysics Model in the Study of Straw Addition Effects on Dewatering Performance of Residual Sludge During Freeze-Thaw Cycles
By Guo Rui Verified, Wang Wei, Wang Yao, Chi Rui Guang| preprints.org@ You are already at the latest version Freeze-thaw (F/T) technology is an environmentally friendly and efficient method for residual sludge treatment. This study investigates the enhancement of sludge de-watering performance through the addition of straw during F/T cycles. A mathemati-cal model was established using the Box-Behnken central composite design and vali-dated via COMSOL Multiphysics simulations.
By Báo Nhân Dân, Guo Rui Verified, HOU Daorong| zgsydw.cnjournals.com@ 摘要: 目的 探究角蛋白17(keratin 17,Krt17)基因敲除对糖尿病小鼠创面愈合的影响。 方法 取6 周龄野生型小鼠和Krt17 基因敲除小鼠,利用60%高脂饲料喂养4 周和腹腔注射链脲佐菌素(40 mg/ (kg·d),连续5 d)联合诱导建立糖尿病小鼠模型;于造模成功后1 周,小鼠异氟烷全身麻醉,背部剃毛,用6 mm 环钻制造在体的皮肤圆形损伤;于制造创面后第8 天,利用Western blot 和免疫荧光染色检测KRT17 在创面近端中的表达和定位及病理组织学分析;并于制造创面后第0、2、4、6和8天拍照记录,计算伤口愈合速率。 结果 在正常生理情况下,KRT17 主要在小鼠毛囊中表达;当皮肤受到损伤时,创面近端的角质形成细胞中KRT17 的表达显著升高;而糖尿病小鼠创面中KRT17 的表达较对照组小鼠显著下调。与野生型小鼠相比,Krt17 基因敲除小鼠的伤口愈合速率显著降低;创面局部炎症反应更持续。 结论 Krt基因敲除加剧了糖尿病小鼠的创面愈合障碍,Krt可能是参与该病理进程的重要调控基因之一。
Application of COMSOL Multiphysics Model in the Study of Straw Addition Effects on Dewatering Performance of Residual Sludge During Freeze-Thaw Cycles
By Guo Rui Verified, Wang Wei, Wang Yao, Chi Rui Guang| preprints.org@ You are already at the latest version Freeze-thaw (F/T) technology is an environmentally friendly and efficient method for residual sludge treatment. This study investigates the enhancement of sludge de-watering performance through the addition of straw during F/T cycles. A mathemati-cal model was established using the Box-Behnken central composite design and vali-dated via COMSOL Multiphysics simulations.
Company Info
South China Morning Post
The South China Morning Post (SCMP) is a prominent English-language news media company based in Hong Kong, established in 1903. It serves as the city's newspaper of record and aims to lead discussions about Hong Kong, Greater China, and Asia. SCMP operates in both digital and print formats, focusing on delivering accurate and in-depth journalism. SCMP has transformed into a multimedia organization with a strong digital presence, providing 24/7 news coverage through its website, mobile apps, and social media. It publishes a daily newspaper with a significant circulation and offers various magazines, including *Cosmopolitan* and *ELLE*. The company covers a wide range of topics, including business, politics, lifestyle, and technology, and employs advanced tools to enhance content accessibility. With offices in Hong Kong, mainland China, and the U.S., SCMP combines local insights with global perspectives, ensuring comprehensive reporting on regional and international issues.
Hong Kong, Hong Kong
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Founded: 1903