Itai Yanai - Profile and Journalist Details
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Verified
Co-Host, Night Science
New York
Beats
mRNA , Biopharmaceutical Development and Manufacturing, Antibodies , Cell and Gene Therapies, Viral Vectors, Vaccines , MAbs
Content
scRNA-seq uncovers the transcriptional dynamics of Encephalitozoon intestinalis parasites in human macrophages - Nature Communications
By Kacie L McCarty, Bo Xia, Nadia L. Almasri, Joseph Sudar, Maelle Aubry, Itai Yanai, Gira Bhabha| Nature Verified AbstractMicrosporidia are single-celled intracellular parasites that cause opportunistic diseases in humans. Encephalitozoon intestinalis is a prevalent human-infecting species that invades the small intestine. Macrophages are potential reservoirs of infection, and dissemination to other organ systems is also observed. The macrophage response to infection and the developmental trajectory of the parasite are not well studied.
By Itai Yanai, Martin Lercher| Nature Verified In reality, research projects grow through an evolutionary process. Variation — the substrate of evolution — is provided through the emergence of new questions and avenues of investigation. The research team must then choose which directions to pursue, a process akin to natural selection1. Along with this evolution at the macro-scale, a much more orderly process is required at the micro-scale. Within each step, thoughtful study design leads to robust experiments and analyses.
scRNA-seq uncovers the transcriptional dynamics of Encephalitozoon intestinalis parasites in human macrophages - Nature Communications
By Kacie L McCarty, Bo Xia, Nadia L. Almasri, Joseph Sudar, Maelle Aubry, Itai Yanai, Gira Bhabha| Nature Verified AbstractMicrosporidia are single-celled intracellular parasites that cause opportunistic diseases in humans. Encephalitozoon intestinalis is a prevalent human-infecting species that invades the small intestine. Macrophages are potential reservoirs of infection, and dissemination to other organ systems is also observed. The macrophage response to infection and the developmental trajectory of the parasite are not well studied.
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Night Science