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Content
Representative Rodent Models for Renal Transporter Alterations in Human Nonalcoholic Steatohepatitis
By Kayla Frost, Joseph L. Jilek, Erica L. Toth, Michael J. Goedken| Drug Metabolism and Disposition (ASPET)@ Thank you for sharing this Drug Metabolism & Disposition article. NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas.
Renal Transporter Alterations in Patients with Chronic Liver Diseases: Nonalcoholic Steatohepatitis, Alcohol-Associated, Viral Hepatitis, and Alcohol-Viral Combination
By Kayla Frost, Joseph L. Jilek, Robert Klein, Shripad Sinari| Drug Metabolism and Disposition (ASPET)@ AbstractAlterations in hepatic transporters have been identified in precirrhotic chronic liver diseases (CLDs) that result in pharmacokinetic variations causing adverse drug reactions (ADRs). However, the effect of CLD on the expression of renal transporters is unknown despite the overwhelming evidence of kidney injury in CLD patients. This study determines the transcriptomic and proteomic expression profiles of renal drug transporters in patients with defined CLD etiology.
Representative Rodent Models for Renal Transporter Alterations in Human Nonalcoholic Steatohepatitis
By Kayla Frost, Joseph L. Jilek, Erica L. Toth, Michael J. Goedken| Drug Metabolism and Disposition (ASPET)@ Thank you for sharing this Drug Metabolism & Disposition article. NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas.
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