Leanne Winner - Profile and Journalist Details
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Leanne Winner
Verified
Host, The Board Table
Raleigh
Beats
infrastructure, banking and insurance the stock market, money market transport and logistics, real estatecapital markets
Product launches
Content
Evaluation of neuroretina following i.v. or intra‐CSF AAV9 gene replacement in mice with MPS IIIA, a childhood dementia
By Helen Beard, Leanne Winner, Andrew Shoubridge, Healthy Microbiome| Wiley Online Library Verified 1 INTRODUCTION Sanfilippo syndrome type A or mucopolysaccharidosis IIIA (MPS IIIA) is a childhood dementia-causing disorder that is presently untreatable.
Evaluation of neuroretina following i.v. or intra‐CSF AAV9 gene replacement in mice with MPS IIIA, a childhood dementia
By Helen Beard, Leanne Winner, Andrew Shoubridge, Healthy Microbiome| Wiley Online Library Verified 1 INTRODUCTION Sanfilippo syndrome type A or mucopolysaccharidosis IIIA (MPS IIIA) is a childhood dementia-causing disorder that is presently untreatable.
Biomarkers for predicting disease course in Sanfilippo syndrome: An urgent unmet need in childhood‐onset dementia
By Leanne Winner, Mary-Louise Rogers, Marten F. Snel, MS-Imaging Facility| Wiley Online Library Verified Mitochondrial dysfunction Corresponding to the reduction in autophagic activity in Sanfilippo, structurally abnormal mitochondria, along with impaired mitochondrial activity, have been measured in MPS IIIC mice (Martins et al., 2015). Mitochondrial budding has also been noted in Sanfilippo human post-mortem brain tissue (Haust, 1968). Furthermore, in MPS IIIC mouse brain synaptosomes, reduced levels of mitochondrial proteins were detected, compared with control (Pará et al., 2021).
Company Info
The Board Table
Great Falls, Montana, United States
+1 406-771-4300