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Agriculture, I Have Covered All Public Issues , Crime, Rural Envoirement, Protest , Political
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Differential effects of conventional transcranial direct current stimulation (tDCS) and high-definition transcranial direct current stimulation (HD-tDCS) of the cerebellum on offset analgesia
By Niamh O'Connor, Hannah BakerIsaac Ashe, Max Wragan, Ruairi O'Flaherty| bioRxiv@ AbstractBackground: Offset analgesia (OA) describes the large decrease in perceived pain in response to a minor decrease in applied painful thermal stimulus. Here non-invasive brain stimulation (NIBS) is used to modulate the cerebellum, since the cerebellum is known to signal sensory prediction errors and implicated in pain processing. Methods: An OA protocol individualized to heat pain threshold (HPT) was applied via TSA-II (Medoc, Israel). NIBS interventions were applied prior to OA.
By Max Wragan, Niamh O'Connor, Hannah J. Ashe, Ruairi O'Flaherty| bioRxiv@ AbstractBackground: Sex differences have been widely demonstrated in both acute and chronic pain. Sex differences may have wider impact on research design and analysis than already established. This study addresses an important methodological aspect with regards to how sex differences could influence the design of standardized experimental pain protocols used to characterize an individuals pain response.
Differential effects of conventional transcranial direct current stimulation (tDCS) and high-definition transcranial direct current stimulation (HD-tDCS) of the cerebellum on offset analgesia
By Niamh O'Connor, Hannah BakerIsaac Ashe, Max Wragan, Ruairi O'Flaherty| bioRxiv@ AbstractBackground: Offset analgesia (OA) describes the large decrease in perceived pain in response to a minor decrease in applied painful thermal stimulus. Here non-invasive brain stimulation (NIBS) is used to modulate the cerebellum, since the cerebellum is known to signal sensory prediction errors and implicated in pain processing. Methods: An OA protocol individualized to heat pain threshold (HPT) was applied via TSA-II (Medoc, Israel). NIBS interventions were applied prior to OA.
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