Roxana Florea - Profile and Journalist Details
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Roxana Florea
Verified
Milan
Beats
marriage, Wellness and wellbeing real life stories,Relationship family relationships, Black Lives Matter politics
theater
Content
Transcriptional changes across tissue and time provide molecular insights into a therapeutic window of opportunity following traumatic stress exposure
By Lauren A McKibben, Meghna Iyer, Ying Zhao, Roxana Florea| bioRxiv@ AbstractUnfortunately, survivors of traumatic stress exposure (TSE) frequently develop adverse posttraumatic neuropsychiatric sequelae (APNS) such as chronic pain and stress/depressive symptoms. Increasing evidence indicates that there is a 'window of opportunity' following TSE in which therapeutic interventions are most effective against APNS, yet mechanisms accounting for this observation are poorly understood.
Acute and early stress axis modulation in joint disease permanently reduces pain and emotional comorbidities
By Sara Hestehave, Roxana Florea, Samuel Singleton, Alexander J.H. Fedorec| bioRxiv@ AbstractChronic secondary musculoskeletal pain affects 20-30% of the population and includes sensory disturbances and emotional comorbidities, such as anxiety and depression, which reduce quality of life. We monitored a pre-clinical model of persistent joint pain for 6 months and found that sensory and functional changes were immediate while anxio-depressive comorbidities appeared from 3 months onwards.
Transcriptional changes across tissue and time provide molecular insights into a therapeutic window of opportunity following traumatic stress exposure
By Lauren A McKibben, Meghna Iyer, Ying Zhao, Roxana Florea| bioRxiv@ AbstractUnfortunately, survivors of traumatic stress exposure (TSE) frequently develop adverse posttraumatic neuropsychiatric sequelae (APNS) such as chronic pain and stress/depressive symptoms. Increasing evidence indicates that there is a 'window of opportunity' following TSE in which therapeutic interventions are most effective against APNS, yet mechanisms accounting for this observation are poorly understood.
Company Info
Milan, Italy