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Samantha Samson
Verified
Senior Reporter, CBC News
Beats
Human rightcultureJustice
Content
An anti-virulence drug targeting the evolvability protein Mfd protects against infections with antimicrobial resistant ESKAPE pathogens
By Samantha Samson Verified, Seav Ly Tran, Lucie Lebreuilly, Delphine Cormontagne| bioRxiv@ AbstractThe increased incidence of antibiotic resistance and declining discovery of new antibiotics have created a global health crisis, especially for the treatment of infections caused by Gram-negative bacteria. Here, we identify and characterize a molecule, NM102, that displays antimicrobial activity exclusively in the context of infection. NM102 inhibits the activity of the non-essential Mutation Frequency Decline (Mfd) protein by competing with ATP binding to its active site.
By Samantha Samson Verified| CBC Sudbury Verified Councillors feel tax lift request 'unfair' | CBC News LoadedSudbury·Sudbury City HallSome city councillors say they feel they were put in a bad position by the City of Lakes Family Health Team Tuesday night. They asked the finance and administration committee to make their Walden, Val Caron and Chelmsford centres Municipal Capital Facilities, which would lift their property taxes.
An anti-virulence drug targeting the evolvability protein Mfd protects against infections with antimicrobial resistant ESKAPE pathogens
By Samantha Samson Verified, Seav Ly Tran, Lucie Lebreuilly, Delphine Cormontagne| bioRxiv@ AbstractThe increased incidence of antibiotic resistance and declining discovery of new antibiotics have created a global health crisis, especially for the treatment of infections caused by Gram-negative bacteria. Here, we identify and characterize a molecule, NM102, that displays antimicrobial activity exclusively in the context of infection. NM102 inhibits the activity of the non-essential Mutation Frequency Decline (Mfd) protein by competing with ATP binding to its active site.
Company Info
CBC News
CBC News is a division of the Canadian Broadcasting Corporation (CBC), established in 1936 to provide a national public broadcasting service in Canada. It is the largest and most comprehensive news service in the country, delivering a wide range of news and information across various platforms. CBC News offers national and local news coverage, operating in over 40 cities across Canada and maintaining international bureaus in major cities like London, Beijing, and Washington. Its services include digital news alerts, television and radio broadcasts, and extensive online content, such as articles, videos, and podcasts. CBC News is known for its in-depth documentaries and investigative journalism, aiming to inform the public and contribute to the understanding of important issues.
Toronto, Ontario, Canada
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