Shaun Lim - Profile and Journalist Details
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Shaun Lim
Verified
Technology Editor, Asia-Pacific Broadcasting
Beats
Business , Features
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Content
Behavioral state and stimulus strength regulate the role of somatostatin interneurons in stabilizing network activity
By Céline Cammarata, Yingming Pei, Brenda C. Shields, Shaun Lim Verified| bioRxiv@ AbstractInhibition stabilization enables cortical circuits to encode sensory signals across diverse contexts. Somatostatin-expressing (SST) interneurons are well-suited for this role through their strong recurrent connectivity with excitatory pyramidal cells. We developed a cortical circuit model predicting that SST cells become increasingly important for stabilization as sensory input strengthens.
By Sasha Burwell, Haidun Yan, Shaun Lim Verified, Brenda C. Shields| bioRxiv@ AbstractWhen animals unexpectedly fail, their dopamine neurons undergo phasic inhibition that canonically drives extinction learning, a cognitive-flexibility mechanism for discarding outdated strategies. However, the existing evidence equates natural and artificial phasic inhibition, despite their spatiotemporal differences. Addressing this gap, we targeted a GABAA-receptor antagonist precisely to dopamine neurons, yielding three unexpected findings.
Behavioral state and stimulus strength regulate the role of somatostatin interneurons in stabilizing network activity
By Céline Cammarata, Yingming Pei, Brenda C. Shields, Shaun Lim Verified| bioRxiv@ AbstractInhibition stabilization enables cortical circuits to encode sensory signals across diverse contexts. Somatostatin-expressing (SST) interneurons are well-suited for this role through their strong recurrent connectivity with excitatory pyramidal cells. We developed a cortical circuit model predicting that SST cells become increasingly important for stabilization as sensory input strengthens.
Company Info
Asia-Pacific Broadcasting
APB+ (Asia-Pacific Broadcasting+) is a prominent media organization and event organizer focused on the broadcast and multimedia industry in the Asia-Pacific region. Established in 1983, it provides news, insights, and industry analysis while hosting the Asia-Pacific Broadcasting+ Awards to celebrate innovation in broadcasting. The organization operates under Asia-Pacific Broadcasting, offering a news platform that publishes articles, interviews, and analyses on broadcast technology and media workflows. APB+ also manages events, including its annual awards ceremony in Singapore, which honors excellence in broadcasting technology and digital innovation. Additionally, it produces white papers and multimedia content that explore advancements in the industry, such as AI-driven production tools. APB+ serves broadcasters, media networks, and technology vendors throughout the region, facilitating knowledge exchange and professional recognition in the evolving broadcast sector.
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Founded: 1983