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Tina Gao
Verified
News Anchor and Reporter, WBZ-AM (Boston, MA)
Boston
Beats
Plus-Sized FashionBeauty Sustainable Living Culture
Content
Identification of functional rare coding variants in IGF-1 gene in humans with exceptional longevity
By Amanat Ali, Zhengdong Zhang, Tina Gao Verified, Sandra Aleksic| bioRxiv@ AbstractDiminished signaling via insulin/insulin-like growth factor-1 (IGF-1) axis is associated with longevity in different model organisms. IGF-1 gene is highly conserved across species, with only few evolutionary changes identified in it. Despite its potential role in regulating lifespan, no coding variants in IGF-1 have been reported in human longevity cohorts to date.
Rare genetic coding variants associated with age-related episodic memory decline implicate distinct memory pathologies in the hippocampus
By Amanat Ali, Sofiya Milman, Erica Weiss, Tina Gao Verified| medRxiv@ The authors have declared no competing interest. This work was supported by R01AG061155 (SM), U19AG056278 (ZDZ), P01AG017242 (ZDZ), and P01AG047200 (ZDZ). I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
Identification of functional rare coding variants in IGF-1 gene in humans with exceptional longevity
By Amanat Ali, Zhengdong Zhang, Tina Gao Verified, Sandra Aleksic| bioRxiv@ AbstractDiminished signaling via insulin/insulin-like growth factor-1 (IGF-1) axis is associated with longevity in different model organisms. IGF-1 gene is highly conserved across species, with only few evolutionary changes identified in it. Despite its potential role in regulating lifespan, no coding variants in IGF-1 have been reported in human longevity cohorts to date.
Company Info
WBZ-AM (Boston, MA)
Boston, United States