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Contributor, Annals of the Rheumatic Diseases
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Impact of quality of life on overall work productivity impairment and activity impairment of patients with systemic lupus erythematosus: the PEONY study
By Yoshiya Tanaka, Yusuke Miyazaki, Shintaro Hirata, Katsuhide Kusaka|The BMJVerifiedIn clinical practice, a lupus low disease activity state (LLDAS) has been proposed as an alternative treatment target for patients with SLE. LLDAS is associated with reduced accrual of organ damage and improvements in quality of life. Patients with SLE in LLDAS experienced a residual disease burden, especially in pain and fatigue, that was associated with activity impairment
Regulation of fibronectin and collagens type I, III and VI by TNF-α, TGF-β, IL-13, and tofacitinib - Scientific Reports
By Martin Pehrsson, Anne-Christine Bay-Jensen, Morten Asser Karsdal, Bent Deleuran, Tue W. Kragstrup, Satoshi KUBO, Yoshiya Tanaka, Frederik S. Gillesberg|NatureVerifiedAbstractUnderstanding how inflammatory cytokines influence profibrogenic wound healing responses in fibroblasts is important for understanding the pathogenesis of fibrosis. TNF-α and IL-13 are key cytokines in Th1 and Th2 immune responses, respectively, while TGF-β1 is the principal pro-fibrotic mediator
Company Info
Annals of the Rheumatic Diseases
Kitakyushu, Fukuoka, Japan
+81 93-603-1611