Yutaka Kawakami - Profile and Journalist Details
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Yutaka Kawakami
Verified
Senior Editor, Immunotherapy journal
Beats
feel-goodHealth care
None, although the above-listed areas are specialties
Content
Brain‐derived neurotrophic factor (BDNF) induces antagonistic action to Nogo signaling by the upregulation of lateral olfactory tract usher substance (LOTUS) expression
By Junpei Matsubayashi, Yuki Kawaguchi, Yutaka Kawakami, Kohtaro Takei| Wiley Online Library Verified ORIGINAL ARTICLE This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record.
GPC1 specific CAR-T cells eradicate established solid tumor without adverse effects and synergize with anti-PD-1 Ab
By Daiki Kato, Takashi Iwata, Yuki Katoh, Haruhiko Kamada, Kouhei Tsumoto, Satoshi Serada, Tetsuji Naka, Takayuki Nakagawa, Yutaka Kawakami, Tomonori Yaguchi, Kenji Morii, Kinya Tsubota, Yoshiaki Takise, Masaki Tamiya, Hiroki Akiba, Ryohei Nishimura| eLife@ Abstract Current xenogeneic mouse models cannot evaluate on-target off-tumor adverse effect, hindering the development of chimeric antigen receptor (CAR) T cell therapies for solid tumors, due to limited human/mouse cross-reactivity of antibodies used in CAR and sever graft-versus-host disease induced by administered human T cells. We have evaluated safety and antitumor efficacy of CAR-T cells targeting glypican-1 (GPC1) overexpressed in various solid tumors.
Brain‐derived neurotrophic factor (BDNF) induces antagonistic action to Nogo signaling by the upregulation of lateral olfactory tract usher substance (LOTUS) expression
By Junpei Matsubayashi, Yuki Kawaguchi, Yutaka Kawakami, Kohtaro Takei| Wiley Online Library Verified ORIGINAL ARTICLE This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record.
Company Info
Immunotherapy journal
Tokyo, Japan
+81 354-27-1845